Vine Age Affects Vine Performance, Grape and Wine Chemical and Sensory Composition of cv. Zinfandel from California

Mendelian randomisation is a technique for assessing causal associations in observational data. Genetic variants associated with the risk factor of interest are regarded similar way to random assignment clinical trial. The difference due genetic variation, however, materially distinct from change any proposed therapeutic intervention and so might affect outcome differently. Consequently, it can be misleading generalise magnitude estimate effect potential on practice. Awareness limitations such estimates important use target based drug development